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In contrast with mouse thymocytes, mouse ES cells include higher levels of total genomic H3K4me3 and have greater H3K4me3 occupancy on the promoter of the pluripotent gene Oct4 forty six In settlement with this, international decreases in H3K4me3 levels happen throughout retinoic acid (RA)-induced [differentiation](http://mtrc.co.kr/bbs/board.php?bo_table=free&wr_id=2578802) of mouse ES cells 47 As well as, there are dynamic adjustments in H3K4me3 profiles at specific units of genes during ES cell differentiation.
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